Commentary on Grebelyet al. (2019): Ending HCV epidemics among people who inject drugs
نویسندگان
چکیده
منابع مشابه
HCV in people who inject drugs: a neglected epidemic.
Despite the serious health implications of hepatitis C virus (HCV), especially in the context of concurrent HIV infection, its prevention and management has not been a national health priority in India. With the advent of highly effi cacious direct acting antiviral drugs for HCV that can be administered orally once daily, and activism around the reduction of treatment costs, HCV treatment might...
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INTRODUCTION The offer of pre-exposure prophylaxis (PrEP) is recommended as an additional option for HIV prevention for people at substantial risk of HIV infection as part of combination HIV prevention approaches. Implementing this depends on integrating PrEP in public health programmes that address risky practices with evidence-based interventions, and that operate in an enabling legal and pol...
متن کاملModelling the impact of incarceration and prison-based HCV treatment on HCV transmission among people who inject drugs in Scotland
Background and Aims People who inject drugs (PWID) experience high incarceration rates, and previous incarceration is associated with elevated hepatitis C virus (HCV) transmission risk. In Scotland, national survey data indicate lower HCV incidence in prison than the community (4.3 versus 7.3 per 100 person-years), but a 2.3-fold elevated transmission risk among recently released (< 6 months) P...
متن کاملDrug-drug interactions in the treatment of HCV among people who inject drugs.
Boceprevir and telaprevir are inhibitors and substrates of the cytochrome P450 3A4 family. With the use of these HCV protease inhibitors as part of standard therapy for chronic hepatitis C genotype 1 infection, drug-drug interactions with multiple medications being inductors, inhibitors, or substrates of cytochrome P450 3A4 can be expected. Due to the complexity of these interactions, predictin...
متن کاملHCV prevalence can predict HIV epidemic potential among people who inject drugs: mathematical modeling analysis
BACKGROUND Hepatitis C virus (HCV) and HIV are both transmitted through percutaneous exposures among people who inject drugs (PWID). Ecological analyses on global epidemiological data have identified a positive association between HCV and HIV prevalence among PWID. Our objective was to demonstrate how HCV prevalence can be used to predict HIV epidemic potential among PWID. METHODS Two populat...
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ژورنال
عنوان ژورنال: Addiction
سال: 2018
ISSN: 0965-2140
DOI: 10.1111/add.14427